In the lawless frontier town of Flagstone, Arizona, the arrival of Harmonica's long-lost brother, Frank, sets off a chain reaction of events that will have far-reaching consequences for all involved. As the railroad builders advance unstoppably through the desert on their way to the sea, Jill McBain, a mysterious and enigmatic woman, arrives in Flagstone with the intention of starting a new life. However, her plans are quickly derailed when she discovers that her husband, Henry, has been murdered by a group of outlaws, led by the ruthless Frank. As Jill tries to make sense of the chaos surrounding her, she finds herself drawn into a complex web of alliances and rivalries between various factions vying for control over the town. Enter Harmonica, a mysterious stranger with a deadly reputation and a score to settle with Frank. His motives are shrouded in mystery, but it becomes clear that he is determined to bring Frank to justice, no matter what the cost. As the two men engage in a series of intense showdowns, the stakes become higher, and the fate of Flagstone hangs precariously in the balance. Meanwhile, the enigmatic Major Morton, played by Henry Fonda, arrives on the scene, claiming to be investigating the murder of Henry McBain. However, his true intentions are far from pure, and he quickly becomes embroiled in the conflict between Frank and Harmonica. As tensions build towards a dramatic conclusion, Once Upon a Time in the West becomes a sprawling epic that explores themes of loyalty, betrayal, and redemption. The film's sweeping cinematography, memorable characters, and iconic score by Ennio Morricone all come together to create a cinematic masterpiece that has stood the test of time.